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Anti-urolithiatic activity of hydrogenated naphthol isolated from Aerva lanata (L.) Juss. flower extract

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dc.contributor.author Behera, P.C.
dc.contributor.author Bag, B.P.
dc.contributor.author Ghosh, M.
dc.date.accessioned 2018-10-01T12:26:28Z
dc.date.available 2018-10-01T12:26:28Z
dc.date.issued 2016
dc.identifier.citation Indian Journal Of Traditional Knowledge, 15(3), 2016: 453-459
dc.identifier.issn 0972-5938
dc.identifier.uri http://ore.immt.res.in/handle/2018/2260
dc.description University Grants Commission, India
dc.description.abstract One new hydrogenated naphthol was isolated for the first time from methanolic extract of Aerva lanata (L.) Juss. flowers. The compound was elucidated as (2S.3R) 3-(3-hydroxy-3-methyl pent-4-en-1-y1)-2, 5, 5, 8a tetra-methyldecahydronaphthalene-2-ol. The isolated compound (PC) was screened for anti-urolithiatic activity by ethylene glycol induced urolithiasis in rats. In the present study rats treated with the isolated compound (PC), reported for the first time from this taxon, reduced the deposition of calcium oxalate crystals by increasing their solubility and restoring the normal renal architecture.
dc.language en
dc.publisher National Institute Of Science Communication And Information Resources - NISCAIR
dc.relation.isreferencedby SCI
dc.rights Copyright [2016]. All efforts have been made to respect the copyright to the best of our knowledge. Inadvertent omissions, if brought to our notice, stand for correction and withdrawal of document from this repository.
dc.subject Biological Sciences
dc.title Anti-urolithiatic activity of hydrogenated naphthol isolated from Aerva lanata (L.) Juss. flower extract
dc.type Journal Article
dc.affiliation.author Birla Inst Technol, Dept Pharmaceut Sci & Technol, Ranchi 835215, Jharkhand, India


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