Browsing Institute Publications by Author "Kar, A."

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DNA nanomaterials loaded with curcumin and antimiRNA inhibits cell proliferation: A biophysical and cellular study

Kar, A.; Sundaray, K.; Subudhi, U. (Journal of Drug Delivery Science and Technology, vol.121. 2026: 108277)

Curcumin (Cur) is a class of flavonoids isolated from turmeric (Zingiberaceae family), which has numerous biological applications, including antimicrobial, anti-inflammatory, antioxidant and anticancer effects. Since Cur ...
miRNA-mediated alteration of sulfatase modifying factor 1 expression using self-assembled branched DNA nanostructures

Kumari, K.; Kar, A.; Nayak, A.K.; Mishra, S.K.; Subudhi, U. (RSC Advances, 11(18), 2021: 10670-10680)

Sulfatase enzymes catalyze sulfate ester hydrolysis, thus deficiencies of sulfatases lead to the accumulation of biomolecules resulting in several disorders. One of the important sulfatases is estrone sulfatase that converts ...
Self-assembled DNA nanostructure containing oncogenic miRNA-mediated cell proliferation by downregulation of FOXO1 expression

Kar, A.; Kumari, K.; Mishra, S.K.; Subudhi, U. (Bmc Cancer, 22(1), 2022: 1332)

FOXO1 transcription factor not only limits the cell cycle progression but also promotes cell death as a tumor suppressor protein. Though the expression of FOXO1 is largely examined in breast cancer, the regulation of FOXO1 ...

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